Preventive treatment of refractory chronic cluster headache: systematic review and meta-analysis
Cluster headache (CH) is described by unilateral headaches of high intensity lasting from 15 to 180 min with a frequency of up to 8 attacks per day. A cluster headache is classified as an episodic cluster headache (ECH) when the
The effects of herbal medicine (Jujadokseo-hwan) on quality of life in patients with mild cognitive impairment: Cost-effectiveness analysis alongside randomized controlled trial
Mild cognitive impairment (MCI), the early stage of dementia, needs adequate intervention for symptom management and improving the patient’s quality of life (QoL). Dementia is a global public health issue that imposes a heavy economic burden
Association of Complement and Coagulation Pathway Proteins with Treatment Response in First-Episode Psychosis: A Longitudinal Analysis of the Optimise Clinical Trial
Treatment responses to specific antipsychotic drugs are tricky to predict on clinical grounds alone. The current analysis hypothesizes that the baseline complement pathway activity predicts the treatment response and
Effect of discontinuation of Lemborexant following long-term treatment of insomnia disorder: Secondary analysis of a randomized clinical trial
Although many pharmacologic therapies for insomnia are approved for short-term use, patients may use them chronically. Discontinuation of some hypnotic medications may lead to rebound insomnia or withdrawal
Trial of Endovascular Therapy for Acute Ischemic Stroke with Large Infarct
Background The role of endovascular therapy for acute stroke with a large infarction has not been extensively studied in differing populations. Methods Results Conclusion In this trial, patients with large cerebral infarctions had better outcomes with endovascular therapy administered within 24 hours than with medical management alone but had more intracranial hemorrhages.
Brain tumor segmentation of MRI images: A comprehensive review on the application of artificial intelligence tools
Background Brain cancer is a destructive and life-threatening disease that imposes immense negative effects on patients’ lives. Therefore, the detection of brain tumors at an early stage improves the impact of treatments and increases the patient’s survival rates. However, detecting brain tumors in their initial stages is a demanding task and an unmet need. Methods […]