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Therapy: Neurosurgery

Depression in Major Neurodegenerative Diseases and Strokes: A Critical Review of Similarities and Differences among Neurological Disorders

Depression and anxiety are highly prevalent in most neurological disorders and can have a major impact on the patient’s disability and quality of life. The early detection and treatment of depression simultaneously with the neurological disorder is key

Effect and safety of C7 neurotomy at the intervertebral foramen in patients with chronic poststroke aphasia: a multicentre, randomised, controlled study protocol

Aphasia affects many stroke survivors; therefore, effective treatments are urgently needed. Preliminary clinical findings have suggested an association between contralateral C7–C7 cross nerve transfer and recovery from chronic

Trichotillomania in Dementia: A Case Report and Literature Review

Dementia presents with a variety of psychiatric and behavioral disorders, including psychosis, depression, anxiety, behavioral aggression, and

Effect of Argatroban Plus Intravenous Alteplase vs Intravenous Alteplase Alone on Neurologic Function in Patients with Acute Ischemic Stroke: The ARAIS Randomized Clinical Trial

Previous studies suggested the benefit of argatroban plus alteplase (recombinant tissue-type plasminogen activator) in patients with acute ischemic stroke (AIS). However, strong evidence in trials with large sample sizes

Efficacy and safety of vutrisiran for patients with hereditary transthyretin-mediated amyloidosis with polyneuropathy: a randomized clinical trial

Hereditary transthyretin (ATTR variant) amyloidosis, also called hATTR amyloidosis is a rare, rapidly progressive, debilitating, and fatal disease caused by transthyretin (TTR) gene variants. Misfolded TTR accumulates as amyloid

Efficacy, safety, and tolerability of antidepressants for pain in adults: overview of systematic reviews

hronic pain is common and debilitating, impacting approximately one in five people globally. Musculoskeletal conditions like back pain are generally the most common conditions leading to chronic pain, followed by headache

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