Lack of association between PLA2G6 genetic variation and Parkinson’s disease: a systematic review

INTRODUCTION: The phospholipase A2 Group 6 (PLA2G6, also known as PLA2, PARK14, and iPLA2) gene encodes a group via calcium-independent phospholipase A2. Genetic polymorphism of PLA2G6 has been indicated to be involved in conferring susceptibility for Parkinson’s disease (PD), whereas conclusive results have not been obtained.  OBJECTIVE: To conduct a systematic review to determine if PLA2G6 genetic variation confers greater susceptibility […]