Efficacy, safety, and tolerability of antidepressants for pain in adults: overview of systematic reviews
![](https://sciaxis.org/wp-content/uploads/2023/05/side-view-man-holding-pills-container.jpg)
![](https://sciaxis.org/wp-content/uploads/2023/05/side-view-man-holding-pills-container.jpg)
hronic pain is common and debilitating, impacting approximately one in five people globally. Musculoskeletal conditions like back pain are generally the most common conditions leading to chronic pain, followed by headache