Alterations in Intrinsic Brain Activity of Bipolar Disorder and Major Depressive Disorder

Major Depressive Disorder

Introduction Brain structural and functional alterations in neuronal circuits have been observed in both, bipolar disorder and major depressive disorder. While resting-state functional MRI (rs-fMRI) issues a measure of baseline brain activity and connectivity, amplitude of low frequency fluctuations acts as an indirect measure for spontaneous brain activity. Previously, amplitude of low frequency fluctuations has […]

Comorbid Major Depressive Disorder In Schizophrenic Patients

Introduction Major depressive disorder (MDD) plays a key role in the prognosis of schizophrenia and increases suicidal tendencies while hampering the quality of life. Objective To determine the prevalence of schizophrenia-MDD in stabilized schizophrenia real-world outpatients and to evaluate the associated factors dictating the schizophrenia-MDD prevalence. Study Design A Systematic Review and Meta-Analysis Methods Medline, […]