Review of Alzheimer’s disease drugs and their relationship with neuron-glia interaction
Chronic inflammation in the central nervous system (CNS) is a hallmark of neurodegenerative disorders such as Alzheimer’s disease. The etiology of neurodegeneration is diverse, and evidence indicates that extrinsic variables such as lifestyle and chemical exposures are connected to the development of these disorders. Neurotoxic metals have been linked to AD due to their potential to increase beta-amyloid (Aβ) peptide levels and phosphorylation
Astrocyte-Mediated Inflammation in Bipolar Disorder
Bipolar disorder was found to have a unique inflammation pathway involving astrocytes with higher inflammatory cytokine IL-6. The study involved an in vitro model evaluating inflammation-related phenotypes of astrocytes
Inflammation’s Role in Traumatic Brain Injury- Associated Risk for Neuropsychiatric Disorders
There has been an increasing awareness that traumatic brain injury and concussions substantially increase the risk of developing psychiatric diseases. Even mild traumatic brain injury increases the risk of depression and anxiety diseases
Inflammation and autoimmune myasthenia gravis
Myasthenia gravis (MG) is a neuromuscular autoimmune disorder characterized by chronic but intermittent fatigue of the eye- and general body muscles. Muscle weakness is caused primarily by the binding of an autoantibody to the acetylcholine receptors, resulting in blockage of normal neuromuscular signal transmission. Inflammation has long been regarded as an important contributing factor for […]