Status of epilepsy in the tropics: An overlooked perspective
Epilepsy is one of the most common serious chronic neurological disorders impacting people of all ages globally. It is characterized by recurrent seizures. Approximately 50 million people worldwide have epilepsy. Many
Young Children with Multidrug-Resistant Epilepsy and Vagus Nerve Stimulation: A Case Report
A 4-year-old boy without perinatal asphyxia and familial history of epilepsy began to have ictal seizures from age 14 month, with jerky movement of four limbs and head nodding. Abnormal multifocal discharge and background activity were recorded through electroencephalography, and no pathogenic mutation was found in the whole exome sequencing for the patient and his […]
A New Sub-Scalp EEG Monitoring System
A preliminary study on seizure detection and forecasting with a minimally invasive sub-scalp ultra-long term EEG monitoring device revealed successful and accurate monitoring of seziures comparable with conventional EEG monitoring. Five patients with refractory epilepsy were implanted with sub-scalp devices providing two channels of continuous data from both hemispheres of the brain, captured using a […]
High-frequency oscillations and Spikes to Enhance Localization of Epileptogenic Brain Parts
In epilepsy patients, concurrent high-frequency oscillations and spikes were found to be strong biomarkers forlocalizing epileptogenic brain as non-invasive presurgical diagnostic tools. High-frequency oscillations and spikes were also useful to guide successful neurosurgery. In a study, high-density (76-channel) EEG of 25 patients with temporal lobe epilepsy were recorded during long-term presurgical monitoring. Persistent high-frequency oscillations […]
Elucidating the Effect of Extreme Delta Brush Pattern in Anti-N-Methyl-D- Aspartate (NMDA) Receptor Encephalitis
Introduction Anti-N-methyl-d-aspartate (Anti-NMDA) encephalitis (ANMDARE), an autoimmune initially manifests as viral prodrome progressing to psychiatric symptoms. These lead to movement disorders and/or seizures ultimately progressing to decreased level of consciousness. The extreme delta brush is a pattern usually observed in frontotemporal regions of premature infants. This pattern normally goes off upon anti-epileptic treatment, but it […]
Antiepileptic Drugs Linked to Cardiovascular Events
A study found an increased risk of major cardiovascular events in the people with epilepsy taking antiepileptic drugs. Epilepsy is often associated with increased mortality explained by comorbid conditions, lifestyle factors or cardiovascular events. Antiepileptic drugs are linked to lipid abnormalities, alterations in metabolic pathways, changes in homocysteine and C-reactive protein levels which contribute to […]