The effect of cognitive behavioral therapy on future thinking in patients with major depressive disorder: A randomized controlled trial
Patients suffering from a major depressive disorder commonly indicate pessimistic views toward the future. Pessimistic thinking about the future is one of the cardinal symptoms of major depressive disorder and an important domain
Are antipsychotics useful in treatment-resistant depression?
In the case of antidepressants, it has been seen that one out of three people with a major depressive disease does not experience improvement even after taking sequential courses of antidepressants and develop treatment-resistant depression. Multiple acute-phase studies have shown the effectiveness of antipsychotics in the improvement of depressive symptoms but the clinical improvement that is remission remains limited, and also there are significant side effects when using these medications for a long time. Pragmatic clinical trials are needed to see the effectiveness of atypical antipsychotics with treatment-resistant depression.