Cariprazine on Psychosis: Beyond Schizophrenia – A Case Series

Case presentation:  a 22-year-old male patient, was referred to our Early Intervention in Psychosis (EIP) team by his General Practitioner (GP) doctor. He progressively developed persistent feelings of sadness, a tendency to isolation, a decay in self-care, loss of appetite, significant weight-loss, and suicidal ideation. Medical history: Family history: Clinical Exam Preliminary treatment: Treatment: Clinical […]

Cariprazine as a treatment option for depressive episodes associated with bipolar 1 disorder in adults

Depressive episodes are the most frequent episodes in bipolar disorder. Few treatments, however, have been approved by the FDA for the treatment of bipolar depression. Cariprazine, a broad-spectrum dopamine antagonist/partial agonist with dopamine D3/D2 and serotonin 5-HT1A receptor partial agonist properties, was recently approved. Partial agonism/antagonism at D3 receptors inhibits the activity of somatodendritic D3 […]