Current and Future Nano-Carrier-Based Approaches in the Treatment of Alzheimer’s Disease
It is a very alarming situation for the globe because 55 million humans are estimated to be affected by Alzheimer’s disease (AD) worldwide. This is an urgent reminder for better research and treatment due to the unavailability of a permanent medication for neurodegenerative disorders like AD. There are several novel and conventional formulation
Intranasal Drug Administration in Alzheimer-Type Dementia: Towards Clinical Applications
Alzheimer-type dementia (ATD) treatments face limitations in crossing the blood-brain barrier and systemic adverse effects. Intranasal administration offers a direct route to the brain via the nasal cavity’s olfactory and trigeminal pathways. However, nasal physiology
Advanced MRI in cerebral small vessel disease
Cerebral small vessel disease (cSVD) is a major cause of stroke and dementia. This review summarizes recent developments in advanced neuroimaging of cSVD with a focus on clinical and research applications. These techniques enable progression
Brain-Only Metastasis and 10-Year Survival after Curative Gastric Cancer Resection: A Case Report
A 65-year-old Korean male with a history of gastric cancer underwent a total mastectomy with Roux-en-Y anastomosis and six cycles
Customizing delivery nano-vehicles for precise brain tumor therapy
Tumor relapse induced by extramedullary infiltrate poses the largest threat to patient survival. The central nervous system is one
Infantile Biotin Thiamine Responsive Basal Ganglia Disease
Biotin thiamine responsive basal ganglia disease (BTRBGD) is an inherited autosomal recessive disorder that results from the inability of thiamine to cross the blood–brain barrier. It is considered a treatable condition if vitamin supplementation