A Spectrum of Rare Symptoms
A 23-year-old woman presented with the psychosis, increased appetite along with obsessive symptoms and poor hygiene. She was non-responsive to therapy for obsessive compulsive disorder. Her MRI showed diffuse, bilateral frontal temporal atrophy prominently in subarachnoid spaces, sylvian fissure and ventricles. Her Mini Mental Status Examination (MMSE) score was 13/30 and her Frontal Assessment Battery […]
A Spectrum of COVID-19 Symptoms or Alzheimer’s?
A 67-year-old woman presented with the complaints of memory loss, difficulties in concentration especially during reading and cognitive fatigue after recent recovery from COVID-19 infection. The patient had a history of type 2 diabetes mellitus being managed with metformin. Her laboratory evaluation was normal except mild elevation of C-reactive protein. Her neuropsychological assessment revealed a […]
Advanced Alzheimer’s Disease in an Elderly
An 80-year-old man with Alzheimer’s disease presented with a 4-year decline in episodic memory. Over years, the patient had gradual decline in memory, developed hesitant speech and impaired organizational skills. His family stated that he could not recognize his family members and common objects over past 6 months. His current therapy was donepezil, rivastigmine and […]
Levetiracetam and Lacosamide in epilepsy patients
Introduction Conventional anti‑epileptic first‑line drugs can control the seizures of most patients with epilepsy, but persistent seizures occur in more than 30% of patients. Lacosamide, an antiepileptic drug, has been used as an adjuvant treatment for partial or systemic epilepsy. Objective To evaluate the therapeutic effect of levetiracetam combined with Lacosamide in patients with epilepsy. […]
Management of drug-resistant focal epilepsy with Levetiracetam
Introduction Epilepsy affects over 70 million people worldwide. With the evolving resistance of focal epilepsy, there is need for add-on therapies for better clinical outcomes. Objectives To evaluate the effectiveness of levetiracetam as an add-on treatment for people with drug-resistant focal epilepsy. Search methods The Cochrane Register of Studies (CRS Web, which includes the Cochrane […]
Hypolipidemia is associated with the severity of COVID-19
A study investigated pathological alteration in plasma lipid levels of COVID-19 patients. LDL-c and TC levels were significantly lower in COVID-19 patients as compared with normal subjects. Significant and gradual decreases in levels of LDL-c and TC were observed in all patients. HDL-c levels only decreased significantly in critical cases as compared with levels in […]