Is Adjunctive Interpersonal and Social Rhythm Therapy Beneficial for Patients with Bipolar Disorder?
Interpersonal and social rhythm therapy in the treatment of bipolar disorder can assist patients in reducing the stressors leading to acute episodes. The ideal treatment for bipolar disorder includes treatment of an episode
Effects of Bipolar Disorder and Valproate Treatment on Striatal Dopamine Transporters
The dopamine transporter regulates the reuptake of extracellular dopamine into presynaptic neurons and its dysfunction could lead to mood and behavior abnormalities as observed in bipolar disorder. Previously conducted
Long-Term Management of Bipolar Disorder Using Paliperidone Palmitate
Bipolar disorder patients demonstrate a high rate of medication non-adherence which ranges anywhere between 20% to 60%. Long acting injectable (LAI) drugs are considered to possess the potential to manage this non-adherence
Progression of Retinal Atrophy and Presence of Oligoclonal Bands as Indicators of Cognitive Decline in Multiple Sclerosis
Inflammatory and neurodegenerative pathological features lead to cognitive impairment in 50–70% of multiple sclerosis patients. Biomarkers of axonal damage in multiple sclerosis include macular ganglion cell layer and retinal nerve fiber
Immunomodulatory Effects of Sunlight in Multiple Sclerosis
Multiple sclerosis, a neuroinflammatory disease characterized by demyelinating lesions, often has a relapsing-remitting progression. Environmental factors such as poor sunlight exposure is believed to contribute to
Astrocyte-Mediated Inflammation in Bipolar Disorder
Bipolar disorder was found to have a unique inflammation pathway involving astrocytes with higher inflammatory cytokine IL-6. The study involved an in vitro model evaluating inflammation-related phenotypes of astrocytes