A Novel PSEN1 Variant Leading to Posterior Cortical Atrophy: A Case Report
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that affects millions of people worldwide. The disease is characterized by the deposition in the brain of amyloid-β (Aβ) plaques and neurofibrillary tangles, mainly
A Case Report of a 37-Year-Old Alzheimer’s disease Patient with Prominent Striatum Amyloid Retention
The amyloid deposition has long been considered one of the pathognomonic markers of Alzheimer’s disease (AD). Moreover, disruption in the amyloid hypothesis has been frequently discussed as an important target of intervention
Neuroimaging in Alzheimer’s disease for Early Diagnosis: A Comprehensive Review
Alzheimer’s disease (AD), a progressive neurodegenerative disorder, is the most common cause of dementia in older adults, distinguished by neurofibrillary tangles (NFTs) and neurotic plaques formed as a result of the accumulation of amyloid-beta (Aβ) peptides, most commonly in the neocortical structures and medial temporal lobe of the brain. Advanced age is the single most significant risk factor for AD. Symptoms generally appear after the age of
Prefrontal EEG slowing, synchronization, and ERP peak latency in association with predementia stages of Alzheimer’s disease
Dementia is a group of neurodegenerative disorders that affect human cognition and behaviors, like the decline in memory, changes in personality and behavior, and impairment in reasoning and language ability. Alzheimer’s disease (AD) is the main cause of
Alzheimer’s disease: An Updated Overview of Its Genetics
Alzheimer’s disease (AD) is a neurodegenerative disorder and represents the most common form of dementia. At present, an estimated 50% of million people worldwide suffer from some form of dementia. AD is characterized by chronic and acquired memory impairment and
Review of Alzheimer’s disease drugs and their relationship with neuron-glia interaction
Chronic inflammation in the central nervous system (CNS) is a hallmark of neurodegenerative disorders such as Alzheimer’s disease. The etiology of neurodegeneration is diverse, and evidence indicates that extrinsic variables such as lifestyle and chemical exposures are connected to the development of these disorders. Neurotoxic metals have been linked to AD due to their potential to increase beta-amyloid (Aβ) peptide levels and phosphorylation