The repetitive transcranial magnetic stimulation in Alzheimer’s disease patients with behavioural and psychological symptoms of dementia: a case report

A 73-year-old woman presented with complaints of cognitive function decline. She usually lost everything, cooked in the wrong order, and forgot where things were put. Patients and their families do not pay attention to this phenomenon. The patient’s cognitive function continued to decline, gradually she started to dress incorrectly and can’t recognize familiar people and she can’t go home on her own. The patient indicated behavioral and psychological symptoms of dementia, such as abnormal restlessness at night, abnormal noise during the day, beating and abusing family members, irritability, gibberish, unexplained fear, and crying, delusion, auditory hallucinations, agitation, and other phenomena. The patient was started on Donepezil hydrochloride. Due to persistent chest tightness, the patient returned to the hospital the day after, and the treatment was changed.

Results

Repetitive transcranial magnetic stimulation maintenance medication (Memantine Hydrochloride Risperidone) rTMS (Repetitive transcranial magnetic stimulation) is a technique that has been successfully used to treat the symptoms of various neurological and psychiatric disorders including Alzheimer’s disease, depression, and schizophrenia. rTMS has been used in clinical practice as a treatment with high safety and fewer side effects. After treatment, the patient’s cognitive function improved.

Repetitive transcranial magnetic stimulation maintenance medication (Memantine Hydrochloride Risperidone)

rTMS (Repetitive transcranial magnetic stimulation) is a technique that has been successfully used to treat the symptoms of various neurological and psychiatric disorders including Alzheimer’s disease, depression, and schizophrenia. rTMS has been used in clinical practice as a treatment with high safety and fewer side effects. After treatment, the patient’s cognitive function improved.

#1. What treatment should be given as per the condition of the patient?

Finish

Adapted from:

  1. Yang Z, Zhou Y. The repetitive transcranial magnetic stimulation in Alzheimer's disease patients with behavioral and psychological symptoms of dementia: a case report. BMC Psychiatry. 2023 May 23;23(1):354. doi: 10.1186/s12888-023-04864-z. PMID: 37221495; PMCID: PMC10207599