A 17-year-old girl presented with drug-resistant epilepsy since the age of 13. She often experienced impaired awareness seizures which rarely proceeded to bilateral tonic-clonic seizures. EEG had left temporal focal slowing without epileptiform discharges while a week long video-EEG showed no changes but the patient complained of olfactory aura. Her MRI was consisted with dermoid cyst in the temporal region. Her clinical evaluation did not show symptoms of meningitis or rupture of the cyst. Her previous therapies with lacosaminde and levetiracetam had failed to control seizures.
Results
- d) Musicogenic epilepsy
- Musicogenic epilepsy is a rare form of reflex epilepsy demonstrating the extraordinary power of music on the human brain. Such seizures are known to be triggered by the patients’ emotional response to music. Autoimmune encephalitis is also a possible aetiology of musicogenic epilepsy, especially in patients with anti-glutamic acid decarboxylase 65 antibodies. In this case the patient was seronegative indicating that regardless of autoantibody status, autoimmune encephalitis can a potential cause for musicogenic epilepsy. The patient had a cognitive trigger as he lacked any emotional drive associated with the music he was exposed to.
- d) Musicogenic epilepsy
- Musicogenic epilepsy is a rare form of reflex epilepsy demonstrating the extraordinary power of music on the human brain. Such seizures are known to be triggered by the patients’ emotional response to music. Autoimmune encephalitis is also a possible aetiology of musicogenic epilepsy, especially in patients with anti-glutamic acid decarboxylase 65 antibodies. In this case the patient was seronegative indicating that regardless of autoantibody status, autoimmune encephalitis can a potential cause for musicogenic epilepsy. The patient had a cognitive trigger as he lacked any emotional drive associated with the music he was exposed to.
#1. What is the diagnosis of this patient?
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