A Spectrum of Rare Symptoms

Symptoms

A 23-year-old woman presented with the psychosis, increased appetite along with obsessive symptoms and poor hygiene. She was non-responsive to therapy for obsessive compulsive disorder. Her MRI showed diffuse, bilateral frontal temporal atrophy prominently in subarachnoid spaces, sylvian fissure and ventricles. Her Mini Mental Status Examination (MMSE) score was 13/30 and her Frontal Assessment Battery (FAB) scores was 6/18. Her speech showed increased latency, high pitch and had hallucination of insects. Her physical examination normal and she was receiving thyroxine supplementation for thyroid abnormalities. She had no neuropsychiatric history.

Results

b) Young onset fronto-temporal dementia
  • There is an emergence of novel presenting symptoms are like psychosis and mental illness in dementia patients rather than cognitive dysfunction and memory loss. Usually, frontotemporal dementia does not present with psychotic features, however, theare are a few cases of young patients with schizophrenia like features having underlying young onset dementia. These neuropsychological dysfunction are attributed to the frontotemporal theory for the psychopathology in schizophrenia. Clinicians must be conscious of such diagnosis of young onset frontotemporal dementia while evaluating young psychotic patients.

b) Young onset fronto-temporal dementia

  • There is an emergence of novel presenting symptoms are like psychosis and mental illness in dementia patients rather than cognitive dysfunction and memory loss. Usually, frontotemporal dementia does not present with psychotic features, however, theare are a few cases of young patients with schizophrenia like features having underlying young onset dementia. These neuropsychological dysfunction are attributed to the frontotemporal theory for the psychopathology in schizophrenia. Clinicians must be conscious of such diagnosis of young onset frontotemporal dementia while evaluating young psychotic patients.

#1. With what condition are her neuropsychiatric symptoms associated?

Finish

Adapted from:

  1. Roy P, Chaudhari P, Pandit HM,Shah N, Karia S, De Sousa A. Young onset fronto-temporal dementia – A case report. Telangana J Psychiatry.2020;6(1):99-101.