Epilepsy is one of the most common serious chronic neurological disorders impacting people of all ages globally. It is characterized by recurrent seizures. Approximately 50 million people worldwide have epilepsy. Many investigations have analyzed the molecular mechanisms and clinical facets of epilepsy; however, the treatment gap exists in some particular areas. In the tropics, the distinct geographical and ecological conditions and a lack of medical resources result in neglect or delay of diagnosis for people with epilepsy (PWE). The majority of studies have shown that most tropical countries have a high incidence of epilepsy. Thus, in the face of various difficulties, a lot of work is needed to improve the economic level, improve health policies, promote the allocation of medical resources, improve health conditions in tropical areas, adopt effective prevention methods, and form a standardized management system.
