Complete agenesis of corpus callosum with a rare neuropsychiatric presentation: A case report
Agenesis of the corpus callosum (ACC) is a rare phenomenon that might be associated with neuropsychiatric disorders
Role of serum growth factors in Schizophrenia
Schizophrenia is a neurodevelopmental disorder and the growth factors (EGF, VEGF, FGF-2, TGF-α, PDGF-AA, PDGF-AB/BB) plays an important role in the development of schizophrenia symptoms. Growth factors are cytokine molecules that are important in the regulation of tissue nucleation, cell development, survival, and migration of all tissues in organisms including the brain and nervous system.
TGF-α, and PDGF-AA serum levels are significantly elevated in schizophrenia. FGF-2 levels are positively correlated with the duration of schizophrenia.
Functional Movement Disorder and Parkinson’s Disease Comorbidity: A Case Report
Case Presentation A 22-year-old male patient presented to the emergency room of hospital with chief complaints of restlessness, an intolerable urge to pace around, suspiciousness, and sleep disturbances in the form of late-onset and midnight awakenings for four days. Medical History Family History Clinical Exam Treatment Clinical Outcome Careful observation, interviews, and periodic mental status […]
Ultra-Long-Acting Oral Antipsychotic for Treatment of Schizophrenia
A new phase II study suggested improved quality of life and treatment adherence in schizophrenic patients with a novel, ultra-long-acting formulation of risperidone (LYN-005). The study comprised of 32 schizophrenia patients received immediate-release (IR) risperidone 2 mg or 4 mg and were randomized to either of the four groups, IR risperidone-matched placebo and LYN-005 at […]
FDA Approves Another Drug for Schizophrenia and Bipolar I Disorder
For the management of schizophrenia and bipolar I disorder, US FDA recently approved a once-daily oral combination medication of olanzapine and samidorphan. Olanzapine on its own is highly efficacious but demonstrates side effects such as weight gain. In the ENLIGHTEN-2 study, the combination has proven its efficacy along with significantly less weight gain than olanzapine […]