Peripheral neuropathy in Parkinson’s disease: prevalence and functional impact on gait and balance
Peripheral neuropathy is a common problem in patients with Parkinson’s disease. Peripheral neuropathy’s prevalence in Parkinson’s disease varies between 4.8-55% compared with 9% in the general population. It stays unclear whether
Integrated Outpatient Palliative Care Versus Standard Care In Patients With Parkinson Disease And Related Disorders
Parkinson’s disease (PD) affects 1 – 2% of the population above 65 years of age and has consequences on quality of life (QoL). PD and related disorders (PDRD) tend to have additional symptoms contributing to worse prognosis
Recognizing The Risk Loci For Parkinson’s Disease In Asians
Previous studies have identified several familial PD genes such as SNCA and LRRK2 in the European population. However, records of any comparative study to evaluate the extent of genetic risk between the Asian and European
Functional Movement Disorder and Parkinson’s Disease Comorbidity: A Case Report
Case Presentation A 22-year-old male patient presented to the emergency room of hospital with chief complaints of restlessness, an intolerable urge to pace around, suspiciousness, and sleep disturbances in the form of late-onset and midnight awakenings for four days. Medical History Family History Clinical Exam Treatment Clinical Outcome Careful observation, interviews, and periodic mental status […]
Parkinsonism caused by adverse drug reactions
A 29-year-old Nigerian Edo woman, presented with a five-day history of tremor of her fingers and head at rest, with associated drooling of saliva from her mouth. There was no history of fever, vomiting, headache, dyspeptic symptoms, or any other neurological symptoms, although she reported dizziness. She had not used any drugs in the preceding […]
Lack of association between PLA2G6 genetic variation and Parkinson’s disease: a systematic review
INTRODUCTION: The phospholipase A2 Group 6 (PLA2G6, also known as PLA2, PARK14, and iPLA2) gene encodes a group via calcium-independent phospholipase A2. Genetic polymorphism of PLA2G6 has been indicated to be involved in conferring susceptibility for Parkinson’s disease (PD), whereas conclusive results have not been obtained. OBJECTIVE: To conduct a systematic review to determine if PLA2G6 genetic variation confers greater susceptibility […]