An Umbrella of Clinical Manifestations
A 7-year-old boy was presented with a diagnosis of attention deficit hyperactivity disorder. The patient was hyperactive and had the impression of difficulty with eye contact. He also had mild motor tics disorder and IQ of 76%. At 9 years, the mother reported that he turned speechless, especially when it came to interacting with strangers. […]
Antiepileptic Drugs Linked to Cardiovascular Events
A study found an increased risk of major cardiovascular events in the people with epilepsy taking antiepileptic drugs. Epilepsy is often associated with increased mortality explained by comorbid conditions, lifestyle factors or cardiovascular events. Antiepileptic drugs are linked to lipid abnormalities, alterations in metabolic pathways, changes in homocysteine and C-reactive protein levels which contribute to […]
Brivaracetam FDA-Approved for Pediatric Seizures
Brivaracetam, available in the form of tablets, oral solution and intravenous fluid (IV) is now FDA-approved for the treatment of partial-onset seizures in children as young as one month. Brivaracetam IV formulation is the only IV formulation approved in last 7 years to treat partial-onset seizures in children one month of age and older. As […]
Association between COVID-19 and New-onset Epileptic Seizures
Name – American Academy of Neurology Annual Meeting (AAN 2021) (April 17 – April 22, 2021) Mode – Virtual A retrospective study conducted on COVID-19 patients, found a three times higher risk of novel seizures in those without a known history of epilepsy. Patients with new-onset seizures had longer hospital stays by 15 days and […]
Predictors of Late Seizure Relapse After Epilepsy Surgery
Based on the findings of a new study, incomplete resection and epilepsy onset during first year of life were found to be key predictors of late seizure relapse following epilepsy surgery. In this retrospective analysis, around 99 patients who experienced a seizure relapse after 2 years of seizure freedom were matched with controls having long-term […]
Cannabidiol Gel for Children with Encephalopathies
In children with developmental and epileptic encephalopathies, use of topical cannabidiol gel along with antiseizure therapy can improve quality of life. The safety and tolerability of cannabidiol gel was studied on 48 children, aged 3 to 13 years, in an open-label, non-randomized controlled trial. After the initial month of baseline and titration period, patients were […]