Epilepsy Talks – Season 1
Our series includes in-depth discussions of complex epilepsy cases, presented by experts in the field. Each episode is tailored to provide you with a comprehensive understanding of the patient’s medical history, diagnosis, treatment, and outcomes.
Young Children with Multidrug-Resistant Epilepsy and Vagus Nerve Stimulation: A Case Report
A 4-year-old boy without perinatal asphyxia and familial history of epilepsy began to have ictal seizures from age 14 month, with jerky movement of four limbs and head nodding. Abnormal multifocal discharge and background activity were recorded through electroencephalography, and no pathogenic mutation was found in the whole exome sequencing for the patient and his […]
A New Sub-Scalp EEG Monitoring System
A preliminary study on seizure detection and forecasting with a minimally invasive sub-scalp ultra-long term EEG monitoring device revealed successful and accurate monitoring of seziures comparable with conventional EEG monitoring. Five patients with refractory epilepsy were implanted with sub-scalp devices providing two channels of continuous data from both hemispheres of the brain, captured using a […]
High-frequency oscillations and Spikes to Enhance Localization of Epileptogenic Brain Parts
In epilepsy patients, concurrent high-frequency oscillations and spikes were found to be strong biomarkers forlocalizing epileptogenic brain as non-invasive presurgical diagnostic tools. High-frequency oscillations and spikes were also useful to guide successful neurosurgery. In a study, high-density (76-channel) EEG of 25 patients with temporal lobe epilepsy were recorded during long-term presurgical monitoring. Persistent high-frequency oscillations […]
Elucidating the Effect of Extreme Delta Brush Pattern in Anti-N-Methyl-D- Aspartate (NMDA) Receptor Encephalitis
Introduction Anti-N-methyl-d-aspartate (Anti-NMDA) encephalitis (ANMDARE), an autoimmune initially manifests as viral prodrome progressing to psychiatric symptoms. These lead to movement disorders and/or seizures ultimately progressing to decreased level of consciousness. The extreme delta brush is a pattern usually observed in frontotemporal regions of premature infants. This pattern normally goes off upon anti-epileptic treatment, but it […]
Dermoid Cyst Concomitant with Focal Cortical Dysplasia
A 17-year-old girl presented with drug-resistant epilepsy since the age of 13. She often experienced impaired awareness seizures which rarely proceeded to bilateral tonic-clonic seizures. EEG had left temporal focal slowing without epileptiform discharges while a week long video-EEG showed no changes but the patient complained of olfactory aura. Her MRI was consisted with dermoid […]