Alterations in Intrinsic Brain Activity of Bipolar Disorder and Major Depressive Disorder
Introduction Brain structural and functional alterations in neuronal circuits have been observed in both, bipolar disorder and major depressive disorder. While resting-state functional MRI (rs-fMRI) issues a measure of baseline brain activity and connectivity, amplitude of low frequency fluctuations acts as an indirect measure for spontaneous brain activity. Previously, amplitude of low frequency fluctuations has […]
Vitamin D Linked to Severity of Bipolar Disorder
Name – European Psychiatric Association (EPA) 2021 Congress (April 10 – April 13, 2021) Mode – Virtual The findings of a research, which suggested that calcium imbalance might impact the long-term outcome of bipolar disorder, was presented at the virtual European Psychiatric Association (EPA) 2021 Congress. It is known that vitamin D regulates the biosynthesis […]
Treat Insulin Resistance for Improvement in Treatment Resistant Bipolar Depression
Name – American Society of Clinical Psychopharmacology (ASCP) 2021 Annual Meeting (June 01 – June 04, 2021) Mode – Virtual A study suggesting treatment insulin resistance may improve symptomatic, treatment-resistant bipolar depression was presented at the virtual American Society of Clinical Psychopharmacology 2021 Annual Meeting. Type 2 diabetes mellitus and insulin resistance affects more than […]
FDA Approves Another Drug for Schizophrenia and Bipolar I Disorder
For the management of schizophrenia and bipolar I disorder, US FDA recently approved a once-daily oral combination medication of olanzapine and samidorphan. Olanzapine on its own is highly efficacious but demonstrates side effects such as weight gain. In the ENLIGHTEN-2 study, the combination has proven its efficacy along with significantly less weight gain than olanzapine […]