Adjunctive lumateperone (ITI-007) in the treatment of bipolar depression: Results from a randomized placebo-controlled clinical trial
Bipolar disorder is a chronic disorder characterized by a significant disease burden. While many agents effectively treat symptoms of mania, treatments for depressive episodes associated with bipolar disorder are limited. Lumateperone, a mechanistically
Is Adjunctive Interpersonal and Social Rhythm Therapy Beneficial for Patients with Bipolar Disorder?
Interpersonal and social rhythm therapy in the treatment of bipolar disorder can assist patients in reducing the stressors leading to acute episodes. The ideal treatment for bipolar disorder includes treatment of an episode
Effects of Bipolar Disorder and Valproate Treatment on Striatal Dopamine Transporters
The dopamine transporter regulates the reuptake of extracellular dopamine into presynaptic neurons and its dysfunction could lead to mood and behavior abnormalities as observed in bipolar disorder. Previously conducted
Astrocyte-Mediated Inflammation in Bipolar Disorder
Bipolar disorder was found to have a unique inflammation pathway involving astrocytes with higher inflammatory cytokine IL-6. The study involved an in vitro model evaluating inflammation-related phenotypes of astrocytes
A rare clinical presentation after COVID-19 infection: Manic episode with psychotic features
A 58-year-old male with no previous mental illness or substantial psychiatric history was admitted with complaints of sudden onset of altered behavior including increased activity and energy, unusual talkativeness,
Case Report: Famotidine for Neuropsychiatric Symptoms in COVID-19
Case Presentation An 18-year-old man presented for psychiatric evaluation with complaints of “I’ve been anxious, irritated and sad most of the time…” and “…inability to get motivated/concentrate and retain information.” Other Symptoms Mentioned Medical History Timeline Of Clinical Case History Clinical Exam Diagnosis Treatment Follow Up 1 Week Later After 3 Weeks At 4 Weeks […]