Hearing impairment has been recently identified as a major modifiable risk factor for cognitive decline in later life and has been becoming of increasing scientific interest. Sensory and cognitive decline are connected by complex bottom-up and top-down processes, a sharp distinction between sensation, perception, and cognition is
Alzheimer-type dementia (ATD) treatments face limitations in crossing the blood-brain barrier and systemic adverse effects. Intranasal administration offers a direct route to the brain via the nasal cavity’s olfactory and trigeminal pathways. However, nasal physiology
Depression and anxiety are highly prevalent in most neurological disorders and can have a major impact on the patient’s disability and quality of life. The early detection and treatment of depression simultaneously with the neurological disorder is key
Over the last two decades, hematopoietic stem cell transplantation (HSCT) has been explored as a potential therapeutic strategy for autoimmune diseases refractory to conventional treatments, including neurological disorders. Although both autologous (AHSCT) and allogeneic HSCT (allo-HSCT) were investigated, AHSCT was
The thymus is the primary lymphoid organ designated to the adaptive humoral immunity construction. It guarantees immune self-tolerance by operating the positive and negative selection of the T cells during their development and maturation, avoiding autoimmune
The coronavirus disease 2019 (COVID-19) pandemic has had a huge impact on practically every aspect of daily life, and those with neuromuscular disorders have certainly not been spared. Early in the pandemic, the heterogeneity of disease was vast. The majority
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