Positive changes to written language following phonological treatment in logopenic variant primary progressive aphasia: Case report

Overview

Introduction

Phonological impairment contributes to deficits in repetition and spoken naming in the logopenic variant primary progressive aphasia (lvPPA).

Case Presentation

A 71-year-old right-handed native English speaker with 16 years of education presented with complaints of language impairment, word-finding difficulties with unimpaired speech production, and relatively preserved grammatical construction of sentences.

Physical Examination

  • Based on the results from neuroimaging and neuropsychological evaluation the patient received a diagnosis of lvPPA.
  • A PET (positron emission tomography) scan indicated asymmetric temporoparietal hypometabolism more pronounced in the left hemisphere, consistent with lvPPA.

Clinical Examination

  • The patient’s primary complaints were trouble with word-finding, spelling, and remembering instructions.
  • The patient reported that she had been experiencing language difficulty for about 15 months.

Treatment

  • The patient received behavioural treatment to strengthen phonological skills to provide stronger support for spoken and written language.
  • Phonological treatment focused on sound blending skills.

Clinical Outcome

  • The patient reported greater confidence in her writing.
  • The patient also shared that she had begun writing more at home (notes, emails).
  • The patient improved phonological skills in response to behavioral treatment

Adapted from:

  1. Nickels K, Beeson PM, Rising K, Jebahi F, Kielar A. Positive changes to written language following phonological treatment in logopenic variant primary progressive aphasia: Case report. Front Hum Neurosci. 2023 Jan 25;16:1006350. doi: 10.3389/fnhum.2022.1006350. PMID: 36760227; PMCID: PMC9905434