Alzheimer’s disease: An Updated Overview of Its Genetics
Alzheimer’s disease (AD) is a neurodegenerative disorder and represents the most common form of dementia. At present, an estimated 50% of million people worldwide suffer from some form of dementia. AD is characterized by chronic and acquired memory impairment and
Review of Alzheimer’s disease drugs and their relationship with neuron-glia interaction
Chronic inflammation in the central nervous system (CNS) is a hallmark of neurodegenerative disorders such as Alzheimer’s disease. The etiology of neurodegeneration is diverse, and evidence indicates that extrinsic variables such as lifestyle and chemical exposures are connected to the development of these disorders. Neurotoxic metals have been linked to AD due to their potential to increase beta-amyloid (Aβ) peptide levels and phosphorylation
Masitinib for mild-to-moderate Alzheimer’s disease: results from a randomized, placebo-controlled, phase 3, clinical trial
Alzheimer’s disease (AD) is a progressive neurodegenerative disease and the main cause of dementia, with an estimated prevalence of 50 million people worldwide that is projected to triple by 2050. Masitinib is an orally administered
Dimethyl Fumarate as Potential Treatment for Alzheimer’s Disease: Rationale and Clinical Trial Design
Alzheimer’s Disease (AD) is a debilitating disease that leads to severe cognitive impairment and functional decline.NRF-2 has been identified in modulating the effects of inflammation and oxidative stress in AD. Activation of NRF-2 leads to an increased
Histone Modifications in Alzheimer’s disease
Alzheimer’s disease is the most common neurodegenerative disorder and the most frequent cause of dementia among the elderly population. The extensive and progressive neuronal loss in the cerebral cortex of Alzheimer’s disease patients, along
Switching attention deficits in post-stroke individuals with different aphasia types
People with aphasia (PWA) also have deficits in attention, thinking, memory, and executive functions. Moreover, s growing body of literature indicates specific attention deficits in some PWA. These cognitive deficits, especially problems