Efficacy, safety, and tolerability of antidepressants for pain in adults: overview of systematic reviews


hronic pain is common and debilitating, impacting approximately one in five people globally. Musculoskeletal conditions like back pain are generally the most common conditions leading to chronic pain, followed by headache
Preventive treatment of refractory chronic cluster headache: systematic review and meta-analysis


Cluster headache (CH) is described by unilateral headaches of high intensity lasting from 15 to 180 min with a frequency of up to 8 attacks per day. A cluster headache is classified as an episodic cluster headache (ECH) when the