Preventive Approaches for Post-Stroke Depression: Where Do We Stand? A Systematic Review
Background Post-stroke depression (PSD) occurs in one-third of stroke survivors, leading to a substantial decrease in quality of life as well as delayed functional and neurological recovery. Early detection of patients at risk and initiation of tailored preventive measures may reduce the medical and socioeconomic burden associated with PSD. Objective To review the current evidence […]
Motor Functional Characteristics in Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorders: A Systematic Review
Background The development of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASDs) has various influences on physical abilities. Identification of specific physical abilities of people with ADHD/ASDs as biomarkers for diagnosing these conditions is necessary. Therefore, in the present review, we aimed firstly to extract the difference in physical abilities of people with ADHD or […]
Risperidone for Children and Adolescents with Autism Spectrum Disorder: A Systematic Review
Background Various clinical trials suggested that risperidone was beneficial in the treatment of autism spectrum disorder (ASD) in children and adolescents. Objective The aim of this systematic review was to determine the efficacy, acceptability and tolerability of risperidone in the treatment of children and adolescents with ASD. Data Sources The databases of Scopus, PubMed, CINAHL […]
Lack of association between PLA2G6 genetic variation and Parkinson’s disease: a systematic review
INTRODUCTION: The phospholipase A2 Group 6 (PLA2G6, also known as PLA2, PARK14, and iPLA2) gene encodes a group via calcium-independent phospholipase A2. Genetic polymorphism of PLA2G6 has been indicated to be involved in conferring susceptibility for Parkinson’s disease (PD), whereas conclusive results have not been obtained. OBJECTIVE: To conduct a systematic review to determine if PLA2G6 genetic variation confers greater susceptibility […]
Cariprazine on Psychosis: Beyond Schizophrenia – A Case Series
Case presentation: a 22-year-old male patient, was referred to our Early Intervention in Psychosis (EIP) team by his General Practitioner (GP) doctor. He progressively developed persistent feelings of sadness, a tendency to isolation, a decay in self-care, loss of appetite, significant weight-loss, and suicidal ideation. Medical history: Family history: Clinical Exam Preliminary treatment: Treatment: Clinical […]