DEPRESSION IN PATIENTS WITH KNEE OSTEOARTHRITIS
Osteoarthritis (OA) is a prevalent joint disease, characterized by whole joint structural changes, and is considered a serious disease. Studies indicate that chronic pain results in a series of changes, specifically fatigue, and disability which results in depression. Individuals who experienced chronic pain and physical activity limitation are at increased risk of depression. Pain incites […]
Deficiency of vitamin D leads to Alzheimer’s and dementia
Low vitamin D concentrations are associated with prevalent Alzheimer’s dementia and cognitive impairment. 1,25-Dihydroxy vitamin D3 receptor and 1α-hydroxylase, the enzyme responsible for synthesizing the bioactive form of vitamin D, are found throughout the human brain. Alzheimer’s is caused by the abnormal build-up of amyloid plaques. In vitro, vitamin D increases the phagocytic clearance […]