Gut Dysbiosis Markers in Severe Mental Illness

Mental Illness

Introduction Gut dysbiosis has been correlated with innumerable poor health outcomes including severe mental illnesses such as bipolar disorder, depression amongst others. It is believed to trigger a chronic low-grade pro-inflammatory status by increasing the gut-barrier permeability. Based on previous studies, elevated pro-inflammatory cytokine levels have been observed in patients suffering from schizophrenia, depression and […]

Alterations in Intrinsic Brain Activity of Bipolar Disorder and Major Depressive Disorder

Major Depressive Disorder

Introduction Brain structural and functional alterations in neuronal circuits have been observed in both, bipolar disorder and major depressive disorder. While resting-state functional MRI (rs-fMRI) issues a measure of baseline brain activity and connectivity, amplitude of low frequency fluctuations acts as an indirect measure for spontaneous brain activity. Previously, amplitude of low frequency fluctuations has […]

Thyroid Diseases and Restless Legs Syndrome in Multiple Sclerosis Patients

Restless Legs Syndrome

Name – 7th Congress of the European Academy of Neurology (June 19 – June 22, 2021) Mode – Virtual A study concluding that multiple sclerosis patients with thyroid disorder are at higher risk for restless leg syndrome, was presented at 7th Congress of the European Academy of Neurology. Multiple sclerosis, a chronic autoimmune disease, has […]

Biomarkers of Primary Progressive Multiple Sclerosis

Biomarker

Name – 7th Congress of the European Academy of Neurology (June 19 – June 22, 2021) Mode – Virtual CXCL12 and Osteopontin were found to be biomarkers of multiple sclerosis progression as per the new research presented at 7th Congress of the European Academy of Neurology. Primary progressive multiple sclerosis involves degenerative and inflammatory processes […]

Vitamin D Linked to Severity of Bipolar Disorder

Bipolar Disorder

Name – European Psychiatric Association (EPA) 2021 Congress (April 10 – April 13, 2021) Mode – Virtual The findings of a research, which suggested that calcium imbalance might impact the long-term outcome of bipolar disorder, was presented at the virtual European Psychiatric Association (EPA) 2021 Congress. It is known that vitamin D regulates the biosynthesis […]

Treat Insulin Resistance for Improvement in Treatment Resistant Bipolar Depression

Depression

Name – American Society of Clinical Psychopharmacology (ASCP) 2021 Annual Meeting (June 01 – June 04, 2021) Mode – Virtual A study suggesting treatment insulin resistance may improve symptomatic, treatment-resistant bipolar depression was presented at the virtual American Society of Clinical Psychopharmacology 2021 Annual Meeting. Type 2 diabetes mellitus and insulin resistance affects more than […]