Effect of Deoxyribonuclease in the treatment of Alzheimer’s
A 77-year-old man was diagnosed with secondary to late onset Alzheimer’s disease. Fourteen months post the diagnosis, patient began treatment with 10 mg memantine. After thirteen months of treatment, patient’s scores on MMSE and FAST were 10 and 5 respectively. Further, significant deterioration of cognitive function was observed after 3 months. His current MMSE and […]
Parkinson’s Disease with Orthostatic Tremor
A 72-year-old lady presented with 2-year history of unsteadiness on standing. Her Unified Parkinson’s disease rating scale (UPDRS)-III, OFF state score was 21. EMG recording revealed a 15–16 Hz tremor with a burst duration of 25 ms, present on standing and absent at rest and walking. Her auscultation over the gastrocnemius muscle revealed helicopter sign […]
Ultra-Long-Acting Oral Antipsychotic for Treatment of Schizophrenia
A new phase II study suggested improved quality of life and treatment adherence in schizophrenic patients with a novel, ultra-long-acting formulation of risperidone (LYN-005). The study comprised of 32 schizophrenia patients received immediate-release (IR) risperidone 2 mg or 4 mg and were randomized to either of the four groups, IR risperidone-matched placebo and LYN-005 at […]
Incidence of Photosensitive Epilepsy and PCOS in a Case of MERRF
Case Presentation A 19-year-old woman was presented with a generalized tonic clonic seizure followed by severe muscle weakness and muscle ache. Family History Medical History Clinical Exam Diagnosis The patient was diagnosed with myoclonic epilepsy with ragged-red fibers (MERRF). Treatment Follow-up At the age of 20, At the age of 21, At the age […]
Agitation and Sugar-Craving Related to Epilepsy: A Case Report
Case Presentation A 12-year-old boy was presented with difficulty in concentration and regulating emotions, impulse control and regulation of activity and sleep. He was speculated for Attention deficit hyperactivity disorder (ADHD) Medical History Clinical Exam His physical examination revealed: Psychological examination revealed: Test Result Ability test (WISC-IV) Intellectual abilities: Below the normal range for the […]
Occurrence of Probable Parkinson’s Disease After SARS-CoV-2 Infection
Case Presentation A 45-year-old man complained of changed handwriting, difficulties speaking and writing text messages on phone during the 3 week isolation period after an infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). He experienced episodes of tremor in his right hand which persisted even after he returned back home. Medical History Clinical Exam […]